The results, published in the BMJ, indicate that the protective effect is particularly strong among patients who’ve previously suffered stroke and Asian patients, and support the continued use of ACE inhibitors in individuals with only mild unwanted effects who are at threat of pneumonia. Overall, the usage of ACE inhibitors decreased the risk of pneumonia by 34 percent compared with control treatment, and by 30 percent weighed against ARBs . ARBs did not have a significant influence on pneumonia risk compared with control. Related StoriesCombatting viral and bacterial lung attacks with volatile anesthetics: an interview with Dr ChakravarthyAmgen gets positive CHMP views for Kyprolis and BLINCYTO Common ingredient in sunscreen can prevent infections related to medical implantsPneumonia risk can be heightened by other conditions such as stroke.

Using zebrafish is an innovative way to do a structure-activity relationship research – a report that examines a number of analog substances to determine which may be the most selective & most potent, he added. Traditionally, pharmaceutical businesses perform these types of studies in vitro, with isolated cells or proteins. But Hong highlights that in vitro research assess only one dimension of the biology. Compounds which have great activity in vitro frequently fail later because they possess poor selectivity or because they do not have chemical properties that produce them good drugs . The zebrafish assesses selectivity and bioavailability all simultaneously, Hong says.